Tuesday, October 16, 2012

2. The Start Of Chemo


The tests that preceded the treatments to determine the extent of the CLL I have, showed that I had significant lymph node growth and a swollen spleen.  That explained the pain I had in my left side.   My white blood count was well over 300,000 where the average person has a WBC of between 4,000 and 11,000.  Plus other tests to show it was indeed CLL/SLL.

By the way, SLL is short for for Small Lymphatic Lymphoma.  And it and CLL are almost the same disease, but just a little different.  Lucky me, I have both!

The treatment I was put into consisted of a chemotherapy cocktail of Fludarabine, Cyclophosphamide and Rituximab or better known in the world of CLL/SLL as FCR.  Which is currently the standard of care.

The Rituximab, or Rituxan is a special drug.  The first day of it was the worst.  I had a little reaction to it, and well, I now know what a hot dog feels like when its cooked in a microwave.  But each following Rituxan treatment was tolerated a lot better.   The Rituxan is mostly there to treat the lymph nodes or as the doctor called it the bulky part of the disease.  It also helps the Fludarabine and Cycloposphamide which are the actual chemo parts that attack and kills cells in your blood and bone marrow.  It is a indiscriminate killer, and also attacks healthy cells as well as cancer cells.

By the way, an interesting fact of Rituxan is that it is made by fusing parts of a mouse DNA antibody with part of human DNA antibody and is grown in the ovary cells of Chinese hamsters.  Thus the reason many Rituxan veterans call it "Mouse Juice"!

For those of you who have not had chemo before, it’s all done via a I. V. that a cancer nurse pokes into your hand or arm.  Or some people get what is called a port, that will allow for the chemo drugs to be pumped into them without a I. V.

My cancer nurses soon earned a nick name of cancer angels.  These are a very well trained, caring and loyal people.  My wife, who is also my caregiver and my rock, made sure to bring a special treat to them and the staff of the chemo ward on the first day of each round of chemo I underwent.

I started this chemo in October 2009 and finished it in February 2010.  I was announced to be in remission in March 2010.  More on chemo woes later.

Never Ever Give Up!

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